Publication

2019 - Fast-acting small molecules targeting malarial aspartyl proteases, plasmepsins, inhibit malaria infection at multiple life stages.
Singh, S.; Rajendran, V.; He, J.; Singh, A. K.; Achieng, A. O.; Vandana: Pant, A.; Nasamu, A. S.; Pandit, M.; Singh, J.; Quadri, A.; Gupta, N.; Ghosh, P. C.; Singh, B. K.; Latha, N.; Kempaiah, P.; Dunn, B. M.; Pandey, K. C.; Goldberg, D. E.; Singh, A. P.; and Rathi, B.*

ACS Infect. Dis. 2019, 5, 184-198.

2018 - Antimalarials: Review of Plasmepsins as Drug Targets and HIV Protease Inhibitors Interactions.
Miller, W. A.; Teye, J.; Achieng, A.O.; Mogire, R. M.; Akala, H.; Ong'cha, J. M.; Rathi, B.; Durvasula, R.; Kempaiah, P.; Kwofie, S. K.

Curr. Topics Med. Chem. 2018, 18, 2022-2028.

2018 - Characterization of immobilized Tyrosinase--an enzyme that is stable in organic solvent at 100 oC
Wu, L.; Rathi, B.; Chen, Y.; Wu, X.; Liu, H.; Li, J.; Ming, A.; Han, G.

RSC Adv. 2018, 8, 39529-39535.

2018 - Biochemical Characterization of Unusual Cysteine Protease of P. falciparum, Metacaspase-2 (MCA-2)
Kumari, V.; Singh, A. P.; Singh J.; Sharma, R.; Akhter, M.; Mishra, P. K.; Saxena, A. K.; Dixit, R.; Rathi, B.; Katyal, A. and Pandey, K. C.

Mol. Biochem. Parasitol. 2018, 2228-41.

2018 - Antiplasmodial activity of hydroxyethylamine analogs: Synthesis, biological activity and structure activity relationship of plasmepsin inhibitors.
Singh, A. K.; Rajendran, V.; Singh, S.; Kumar, P.; Kumar, Y.; Singh, A.; Miller, W.; Potemkin, V. Poonam; Grishina, M.; Gupta, N.; Kempaiah, P.; Durvasula,R., Singh, B.; Dunn, B. M. and Rathi,B.*

Bioorg. Med. Chem. 2018, 26, 3837-3844.

2018 - Multistage Inhibitors of Malaria Parasite: Emerging Hope for Chemoprotection and Malaria Eradication.
Poonam; Gupta, Y.; Singh, S.; Wu, L.; Rawat, M. and Rathi, B.*

Med. Res. Rev. 2018,38, 1511-1535.

2017 - An Overview of Currently Available Antimalarials.
Gorobets, N.; Yuriy S.; Singh B.; Poonam and Rathi, B.*

Curr. Topics Med. Chem. 2017, 17, 2143-2157

2017 - Synergistic blending of high-valued heterocycles inhibits growth of Plasmodium falciparum in culture and P. berghei infection in mouse model.
Kumar, P.; Achieng, A. O.; Rajendran, V.; Ghosh, P.; Singh, B.K.; Rawat, M.; Perkins, Douglas J.; Kempaiah,P.; Rathi, B.*

Sci. Rep. 2017, 7,6724.

2016 - Magnetic iron oxide nanoparticles encapsulating horseradish peroxidase (HRP): synthesis, characterization and carrier for the generation of free radicals for potential applications in cancer therapy.
Gupta, N.; Gupta, C.; Sharma, S.; Rathi, B.; Sharma, R. K. and Bohidar, H. B.

RSC Adv. 2016, 6, 111099.

2016 - Functionalized Organic Frameworks Explored As Second Order NLO Agents.
Singh, A.; Medviediev, V. V.; Shishkin, O.; Bahadur, V.; Singh, T.; Singh, B. K.; Vijayan, N.; Balachandran, V.; Gorobets, Yu N. and Rathi, B.*

J. Chem. Sci. 2016, 128, 297-309.

2016 - Design, Synthesis and Biological Evaluation of Arylpiperazine Based Novel Phthalimides: Active Inducers of Testicular Germ Cell Apoptosis.
Singh, A.; Bhardwaj, J.; Olival, A.; Kumar, Y.; Podder, A.; Maheshwari, A.; Latha, N.; Singh, B. K.; Tomás, H.; Rodrigues, J.; Rathi, B.*

J. Chem. Sci. 2016, 128, 1245-1263.

2015 - Design, Synthesis and Biological Evaluation of Functionalized Phthalimides: A New Class of Antimalarials and Inhibitors of Falcipain-2, a Major Hemoglobinase of Malaria Parasite.
Singh, A. K.; Rajendran, V.; Ghosh, P. C.; Singh, N.; Latha, N.; Garg, S.; Pandey, K. C.; Singh, B. K.; Rathi, B.*

Bioorg. Med. Chem. 2015, 23, 1817–1827.

2015 - Hydroxyethylamine Based Phthalimides As New Class of Plasmepsin Hits: Design, Synthesis and Antimalarial Evaluation.
Singh, A. K.; Rathore, S.; Tang, Y.; Goldfarb, N. E.; Dunn, B. M.; Rajendran, V.; Ghosh, P. C.; Latha, N.; Singh, B. K. and Rathi, B.*

Plos ONE. 2015, 1e0139347